Extended Data Fig. 3. Evidence for the reliability of protein measurements made using the SOMAscan assay.
a, Distribution of coefficients of variation of all proteins on the SOMAscan assay in each subcohort. b, Spearman’s correlations for all proteins passing QC derived from contemporaneous assay of baseline and two-year samples from 60 participants. c, Scatterplot of pQTL effect size estimates from SOMAscan versus Olink showing all 163 pQTLs tested (top) and the 106 that replicated (bottom). r is Pearson’s correlation coefficient. d, Distribution of inflation factors across proteins that underwent genome-wide association testing, stratified by subcohort and allele frequency (MAF ≥ 5%, MAF < 5%).