Fig. 1.
α3β2 and α3β4 are pharmacologically distinct. Top traces, Current responses of an α3β2-expressing oocyte to 10 μm ACh alone and in combination with 3 μmDHβE (left), and current responses of a different α3β2-expressing oocyte to 1 μm ACh before and after 30 min incubation with 100 nmNBT (right).Bottom traces, Current responses of an α3β4-expressing oocyte to 100 μm ACh alone or in combination with 3 μmDHβE (left), and current responses of a different α3β4-expressing oocyte to 10 μm ACh before and after 30 min incubation with 100 nmNBT (right). ACh application of ∼10 sec is indicated by arrowheads. Scale bars: 150 nA, 10 sec.