Skip to main content
. Author manuscript; available in PMC: 2020 Mar 26.
Published in final edited form as: J Am Coll Cardiol. 2019 Mar 26;73(11):1317–1335. doi: 10.1016/j.jacc.2018.12.054

TABLE 3.

Clustering in Cardiac Imaging

First Author (Ref. #) Assessment Type of Clustering Result
Ernande et al. (27) Left ventricular function Agglomerative Hierarchical Clustering 3 clusters with significantly different echocardiographic phenotypes of type 2 diabetes mellitus.
Sanchez-Martinez et al. (28) Heart failure with preserved ejection fraction Agglomerative Hierarchical Clustering 2 groups to capture healthy and heart failure patients with preserved ejection fraction.
Shah et al. (29) Heart failure with preserved ejection fraction Agglomerative Hierarchical clustering and model-based clustering Hierarchical clustering to conceptualize similar and redundant features of phenotypic features. Model-based clustering with Gaussian distribution identified 3 clusters where cluster 1 had the least severe electric and myocardial remodeling while cluster 3 had the most severe.
Katz et al. (30) Heart failure with preserved ejection fraction Model-based clustering 2 clusters with significantly different phenogroups of hypertensive patients.
Omar et al. (40) Left ventricular diastolic dysfunction Agglomerative Hierarchical Clustering 3 groups corresponding to severity of diastolic dysfunction based on speckle-tracking echocardiography data.
Lancaster et al. (32) Left ventricular diastolic dysfunction Agglomerative Hierarchical Clustering 2 groups with the severity of diastolic dysfunction.
Horiuchi et al. (33) Acute heart failure k-means clustering 3 clusters with vascular failure, renal failure, and older patients with atrial fibrillation and preserved ejection fraction, respectively.
Bansod et al. (34) Endocardial border estimation and ellipse fitting on more than 10 video sequences Density-based spatial clustering of applications with noise Endocardial border estimation using density-based spatial clustering of applications with noise.
Carbotta et al. (35) Indication of coronary heart disease Oblique principal components clustering procedure 2 groups with elevated thyroid parameter with reduced cardiovascular parameter increased metabolic parameter to indicate coronary heart disease.
Peckova et al. (36) Diastolic dysfunction Hierarchical Clustering 2 groups showed no association of deterioration of left ventricular relaxation with a mild-to-moderate decrease in eGFR.