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. 2014 Mar;13(100):99–106. doi: 10.1016/j.ehb.2013.12.002

Table 2.

Results of data simulation showing unbiased estimate from two-stage least-squares regression in the presence of confounding.

Model Beta (95% CI)a
Y on X (linear regression) 0.26 (0.25, 0.28)
Y on X (two stage least squares) −0.29 (−0.37, −0.21)
a

True value of beta from simulation is −0.3.